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Natural Pain Relief

Updated: Jun 25, 2025

Over-the-counter (OTC) pain medications may provide temporary relief, but many people are unaware of their long-term side effects. Regular use can contribute to:

  • Indigestion, stomach ulcers, and gastrointestinal bleeding

  • Gut dysbiosis (imbalanced microbiome) and increased intestinal permeability ("leaky gut")

  • Food sensitivities and autoimmune activation

  • Liver and kidney damage

  • Increased risk of stroke


While there are appropriate times for using OTC medications, they shouldn’t be your everyday solution. Thankfully, there are many evidence-based natural options that support pain relief and reduce inflammation—without the side effects. These options not only alleviate discomfort but also nourish and strengthen the body. Here are some of my favorites:


CBD (Cannabidiol)

CBD is an adaptogen, helping the body return to a state of balance (homeostasis). It's a powerful natural option for pain, inflammation, and stress management.


CBD comes from the hemp plant and contains phytocannabinoids—plant compounds that interact with the body’s endocannabinoid system (ECS), a complex cell-signaling network found in the brain, immune system, digestive tract, and more.


CBD may support:

  • Pain relief and inflammation reduction

  • Immune system regulation

  • Muscle relaxation

  • Mood stability and emotional balance

  • Cognitive function and memory

  • Neuroprotection in conditions like epilepsy, MS, Parkinson’s, and Alzheimer’s

  • Cardiovascular health through reduction of oxidative stress

  • Healthy appetite and digestion

  • Brain cell regeneration and communication

  • Skin conditions like acne

  • Healthy metabolism and weight balance


SPM Supreme (Specialized Pro-Resolving Mediators)

SPMs are unique compounds derived from omega-3 and omega-6 fatty acids. Rather than blocking inflammation (like NSAIDs), SPMs resolve it—helping the immune system shift from inflammation to healing.


SPM Supreme is ideal for:

  • Post-surgical healing

  • Inflammatory Bowel Disease (IBD) and leaky gut

  • Obesity and metabolic inflammation

  • Tissue repair and regeneration

  • Asthma, allergies, and respiratory inflammation

  • Stroke recovery

  • Cognitive decline (dementia, Alzheimer’s)

  • Cardiovascular health (e.g., atherosclerosis)

  • Periodontal disease and oral surgery recovery

  • Arthritis, MS, eczema, and skin conditions

  • Bone health and bone loss prevention

  • Chronic Inflammatory Response Syndrome (CIRS)

  • Healthy immune modulation without suppression


Tip: Use for acute pain and inflammation, then taper as symptoms resolve.


Curcumin/Turmeric

Turmeric contains curcumin, a potent anti-inflammatory compound. I recommend Curcum-Evail by Designs for Health due to its superior bioavailability and combination of three key curcuminoids, plus turmeric oil for enhanced absorption.


Curcumin supports:

  • Antioxidant protection

  • Joint pain, arthritis, and physical wear-and-tear

  • Allergies and asthma

  • Autoimmune modulation (e.g., MS, RA)

  • GI protection and leaky gut healing

  • Cholesterol and cardiovascular support

  • Brain health and neuroprotection

  • Detoxification via liver/gallbladder support

  • Binding of toxic metals

  • Antimicrobial activity

  • Postoperative recovery


Use daily or during flares for acute or chronic inflammation.


Inflammatone

Inflammatone is a broad-spectrum anti-inflammatory formula combining herbs, nutrients, and proteolytic enzymes.


Key ingredients and benefits:

  • Proteolytic enzymes: Break down damaged tissue when taken on an empty stomach

  • Turmeric, Boswellia, Ginger: Target inflammatory pathways

  • Quercetin, Rutin, Rosemary, Resveratrol: Provide antioxidant and cellular protection

Used for:

  • Asthma and allergies

  • Brain injury recovery

  • Post-surgical inflammation

  • Eye health

  • Gout, joint pain, and headaches

  • Periodontal disease

  • Fibromyalgia and Lyme disease

  • PMS and fertility support (especially in endometriosis, fibroids, ovarian cysts)


Omega-3 Fatty Acids (EPA & DHA)

Omega-3s from fish oil—especially the active forms EPA and DHA—play a vital role in reducing systemic inflammation and supporting long-term pain relief. They serve as precursors to Specialized Pro-Resolving Mediators (SPMs), helping the body naturally resolve inflammatory processes.


Benefits of Omega-3s:

  • Joint pain and stiffness (e.g., rheumatoid arthritis, osteoarthritis)

  • Menstrual cramps and hormonal pain

  • Cardiovascular inflammation

  • Mood support, especially for pain-related depression and anxiety

  • Cognitive health and brain protection

  • Support for reducing NSAID use over time


Tip: Choose a high-quality, third-party tested fish oil (like Nordic Naturals or Designs for Health OmegAvail). Aim for a combined EPA + DHA dose of at least 1000–2000 mg daily.


Homeopathic Arnica

Arnica montana is a time-tested natural remedy used for trauma, bruising, and muscle soreness. Homeopathic forms come in oral pellets, topical gels, and creams.


Best Uses for Arnica:

  • Acute injury, swelling, and bruising

  • Post-surgical recovery

  • Overuse injuries and musculoskeletal pain

  • Gentle support for elderly or sensitive individuals


Tip: For acute pain or injury, Arnica 30C or 200C can be taken orally every few hours on day one, then 1–3x/day as needed. Always follow dosing guidelines or consult with your provider.


White Willow Bark

White Willow Bark (Salix alba) is a natural source of salicin, the plant compound that inspired aspirin. It offers anti-inflammatory and analgesic benefits, but without the gastrointestinal irritation common with NSAIDs.


Best Uses for White Willow Bark:

  • Headaches and migraines

  • Menstrual cramps

  • Back pain and muscle aches

  • Joint inflammation and arthritis

  • Occasional fever support


Tip: White willow is available in capsule or tea form. Avoid using alongside aspirin or blood thinners unless under guidance. It may be ideal for patients seeking NSAID alternatives with a gentler approach.


Boswellia

Boswellia is excellent for pain and inflammation, especially in:

  • Osteoarthritis

  • Inflammatory Bowel Disease (IBD)

  • Cartilage support and autoimmune modulation


Bromelain

Found naturally in pineapple, bromelain is a powerful enzyme with pain-relieving and anti-inflammatory properties—comparable to NSAIDs, without the side effects.


Ideal for:

  • Postoperative swelling and inflammation

  • General inflammatory pain


ArthroSoothe Supreme

Designed to nourish joints and connective tissues, ArthroSoothe Supreme supports joint mobility, flexibility, and repair.


It supports:

  • Joint lubrication and collagen integrity

  • Cartilage and tendon health

  • Inflammation reduction

  • Swelling and fluid retention

  • Recovery from joint injuries

  • Antioxidant protection


Especially helpful for those with chronic joint deterioration, arthritis, or injury recovery.


Magnesium

Magnesium is often overlooked but plays a key role in pain regulation, muscle function, and nerve health. Deficiency is common and can contribute to:

  • Headaches and migraines

  • Muscle cramps, twitches, and spasms

  • Fibromyalgia-like pain

  • Sleep disturbances

  • PMS and hormonal tension

  • Stress sensitivity and irritability


Forms like magnesium glycinate or magnesium malate are best for pain and muscle support.


Summary

While pharmaceuticals may provide short-term relief, they often don’t address the root causes of pain. A well-stocked natural medicine cabinet can offer powerful, safe alternatives that support the body’s healing processes, reduce inflammation, and restore balance—without sacrificing your long-term health.


If you’re dealing with pain, consider working with our functional practitioners to develop a personalized plan that includes nutritional, herbal, and lifestyle strategies for natural relief. Everyone is different, please contact us with questions regarding medication interactions and/or which would be the best support for you.


Interested in a more personalized plan? Schedule a FREE 15-Minute consult to discuss what Purely Rooted Nutrition and Wellness can do for you.

Visit our store for more supplement information and purchases.


Turmeric
Turmeric

17 Comments


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